Hyperestrogenism

Hyperestrogenism is an intersex variation classified as the the estrogenic version of hyperandrogenism, representing the excessive amount of estrogen in the body. It can be classified under Aromatase Excess Syndrome.

Symptoms of the variation in AFAB/CTF may consist of menstrual irregularities, amenorrhea, abnormal vaginal bleeding, and enlargement of the uterus and breasts. If left untreated, hyperestrogenism may increase the risk of estrogen-sensitive cancers such as breast cancer later in life. This may also cause them to have labial hypertrophy, due to such strong amounts of hormones. Those with this variation also tend to have early growth spurts and mood swings.

It is important to note that not all the symptoms listed in this page are guaranteed to occur in someone with this variation, as someone may only experience one or several of these symptoms, yet still hold the variation.

Causes
Hyperestrogenism can be caused by ovarian tumors, genetic variations (such as aromatase excess syndrome/familial hyperestrogenism,) or overconsumption of exogenous sources of estrogen which may include medications used in hormone replacement therapy and hormonal contraception.

Liver cirrhosis is another cause, though through lowered metabolism of estrogen, not oversecretion or overconsumption like the aforementioned. It's necessary to know there exist two kinds of hyperestrogenism: Absolute (more concentration than usual of estrogen) and relative (can have a normal concentration of estrogen, but it's higher with respect to progesterone).

Flag
The Hyperestrogenism flag was coined by Reign of the breadsticcs on May 7th of 2021. It has no confirmed meaning.